DNA, RNA and genomic analysis: Gegenees is a software project for comparative analysis of whole genome sequence data and other Next Generation Sequence (NGS) data. The software can e.g. Compare a large number of microbial genomes, give phylogenomic overviews and define genomic signatures unique for specified target groups.
Serial Cloner is a Molecular Biology software. It provides tools with an intuitive interface that assists you in DNA cloning, sequence analysis and visualization. Serial Cloner is freeware. And is available for MacOSX, Windows and Linux. A number of free software programs are available for viewing trace or chromatogram files. Click on the appropriate icon(s) to go to the respective Web page. Mac: Linux: In-browser: 4Peaks: Free -Sequence Scanner: Free -Chromas Lite: Free -. Free Online Oligo Analysis Tools Oligo Calc. COVID-19 research and therapeutic.
This software isfreeware or shareware, only for Macintosh computers! Clicking on thelinks below will start the downloadDNA Strider
A bit dated but still great full featured sequence manipulation application for the mac. Freeware | Amplify v1.2
This software is for use in designing, analyzing, and simulating experiments involving the polymerase chain reaction (PCR). Given a template sequence and two primers, it will predict the possible outputs of the PCR, taking into account also weak matches to the target sequence. Freeware, thanks to Bill Engels | DNAid v1.8
As the author says, 'DNAid is not a heavyweight package which will run your 'just-sequenced gene' through every prediction or analysis algorithm in the known universe.' However, it is a very usefull application that allows to perform all the basic manipulations of DNA sequences such as restriction mapping, translation, reverse-complement and others. Freeware, thanks to Frédéric Dardel | MacPlasmap v1.8.2
It draws, stores, and prints high-quality circular plasmid maps with the data you specify. Fully functional. Shareware! Please read the enclosed documents before using the application | Primers! v1.0
Primers! is a very popular Macintosh utility to aid scientists in picking precisely the PCR oligos which fit their needs.Imput the target sequence and a range of selection, and Primers! will sugest the best PCR primers to amplify the selected region. Shareware at your discretion, thanks to Richard J. Resnick (Apple Pi Software). Please read the 'Read Me' file before using the application. Requires any Macintosh with a Color monitor and System 7 or beyond. | RasMac v2.6
RasMac is the Mac version of RasMol, a molecular graphics freeware program intended for the visualisation of proteins, nucleic acids and small molecules, written by Roger Sayle.You can downlod structural coordinates for a molecule of your choice -FOR INSTANCE HERE-and view, rotate and customize the look of the molecule right on your Mac even with no structural biology background (Thank you Roger Sayle!). Great for educational purposes. An excellent web site maintained by Eric Martz, for download and informations on RasMol and CHIME, a RasMol version designed as browser plug-in, can be found HERE. Before using RasMac, please read the enclosed 'Notice' file | SeqView v1.0.1
SeqVu is an alignment editor with analysis options that allows you to work quickly and simply with multiple sequences. It is ideal for manually correcting and obtaining publication-quality pictures from alignments produced using alignment software such as ClustalV or GCG pileup. Fully functional. Shareware. | Speakquencer v1.4
Speakquencer is a tool for entering and/or verifying nucleotide or amino acid sequence information. The application reads pre-existing sequences or speaks sequence as it is entered form the keyboard. Freeware, thanks to Christian Fritze | Swiss-PdbViewer 4.1 (Macos, Linux, Windows)
Free Molecular visualization software by Nicolas Guex and Manuel C. Peitsch. Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface. For informations, tutorials, and to download the viewer for other platforms (PC, SGI, Linux) visit the Swiss PdbViewer official site at expasy. |
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Downloadother Molecular Biology applications from the MB Shortcuts/JustBio softwaresection- Runs in Windows (XP, Vista, 7, 8, and 10) and Mac (OS X v10.5 and above)
- Highlights restriction sites in the editing window
- Accurately reflects Dam/Dcm blocking of enzyme sites
- Highlights text using pre-defined and custom feature libraries
- Shows translation, Tm, %GC, ORF of selected DNA in real-time
- Reads DNA Strider, Fasta, Genbank and EMBL files
- Saves files as DNA Strider-compatible or Genbank file format
- Highlights and draws graphic maps using feature annotations from genbank and embl files
- Directly BLASTs selected sequence at NCBI or wormbase
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- Text map shows DNA sequence, translation, and features as text-based graphics
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- Creates graphic restriction maps- linear or circular with features indicated
- Connects graphic and text features with hyperlink double click
- Saves graphics as encapsulated postscript or scalable vector graphics
- Copy and save graphics as Windows metafiles (MS Windows only)
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Dna Sequence Editing Software
- Virtual restriction digest
- Draws pre-defined and user-defined DNA ladders
- Connects bands to text by double-click
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- Reads ABI sequencing trace files
- Sequences in ABI traces can be aligned directly to a reference sequence, with the alignment hyperlinked back to te trace.
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- Selects sites matching multiple criteria (union/intersection- cut frequency, site type) in all open windows
- Selects sites that cut more often in one sequence than another (for snip-SNP detection or diagnostic digests)
- Has user defined enzyme grouping to distiguish eg. enzymes currently in stock.
- Allows users to define new enzymes by name and recognition site
- Imports DNA Strider format files (simple enzyme, site lists) available from REBASE
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Free Dna Analysis Software Machine
Other Features: | - Most analysis windows are hyperlinked to their corresponding sequences, including:
- Graphic Maps
- Text maps
- Virtual Digests
- Alignments (including ABI sequences)
- Silent Sites
- Translation
- Primer Find
- Uses custom feature definition libraries, which allow:
- Quick annotation of sequence
- Quick searching and highlighting of all available primers that you (or others) have that hybridize to a sequence
- Sequence to be annotated and visualized in multiple ways quickly and efficiently
- Graphic maps that show primer binding sites and all interesting sequence features
- Translates sequences with optional DNA alignment
- Finds potential primers matching user criteria (length, Tm, %GC, self/other complementarity)
- Aligns two DNA sequences (or any combination of sequence and ABI trace), with the alignment hyperlinked to the original sequence
- Finds translationally silent restriction sites
- Draws graphic ORF maps
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